NEK10

Across TCGA cell cohorts, NEK10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,659 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEK10-associated GO terms across cancer lineages are Plus-end-directed vesicle transport along microtubule, Protein localization to cilium, and Regulation of focal adhesion assembly. Each is linked with NEK10 in more than 9 cancer types. Because this analysis shows association rather than direction, both NEK10-to-partner and partner-to-NEK10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plus-end-directed vesicle transport along microtubule grouped by NEK10-low versus NEK10-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEK10→partner) and Y-score (partner→NEK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Plus-end-directed vesicle transport along microtubule →	+0.376	+0.366	.002	.005	3	10
STOMACH	Protein localization to cilium →	+0.052	+0.828	<.001	<.001	2	10
BONE	Regulation of focal adhesion assembly →	+0.154	+1.168	<.001	<.001	3	9
BONE	Positive regulation of focal adhesion assembly →	+0.211	+1.124	<.001	<.001	3	9
BLOOD_Leukemia	Microtubule polymerization →	+0.109	+0.421	<.001	.001	3	9
BREAST	Centrosome duplication →	+0.088	+0.580	.002	.002	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,659 associations by consensus.

Plus-end-directed vesicle transport along microtubule by NEK10 expression — BLOOD_Leukemia

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