NEIL2

Across TCGA cell cohorts, NEIL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,899 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NEIL2-associated GO terms across cancer lineages are Depyrimidination, Peptidyl-serine phosphorylation, and Peptidyl-serine modification. Each is linked with NEIL2 in more than 12 cancer types. Because this analysis shows association rather than direction, both NEIL2-to-partner and partner-to-NEIL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Depyrimidination grouped by NEIL2-low versus NEIL2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEIL2→partner) and Y-score (partner→NEIL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Depyrimidination →	+0.122	+1.000	.004	.006	2	13
CNS	Peptidyl-serine phosphorylation →	+0.064	+0.688	<.001	<.001	3	11
CNS	Peptidyl-serine modification →	+0.062	+0.650	<.001	<.001	3	11
BREAST	Positive regulation of telomere capping →	+0.110	+1.274	<.001	<.001	3	11
URINARY_TRACT	IMP biosynthetic process →	+0.203	+1.143	.001	<.001	3	10
OVARY	Negative regulation of sister chromatid cohesion →	+0.133	+1.483	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,899 associations by consensus.

Depyrimidination by NEIL2 expression — URINARY_TRACT

Explore this box plot interactively →