NEGR1

Across TCGA cell cohorts, NEGR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,108 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NEGR1-associated GO terms across cancer lineages are Intracellular transport of virus, Transport of virus, and Positive regulation of pinocytosis. Each is linked with NEGR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both NEGR1-to-partner and partner-to-NEGR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular transport of virus grouped by NEGR1-low versus NEGR1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEGR1→partner) and Y-score (partner→NEGR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Intracellular transport of virus →	+0.206	+1.809	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Transport of virus →	+0.206	+1.809	<.001	<.001	3	10
KIDNEY	Positive regulation of pinocytosis →	+0.089	+1.901	.002	.002	3	10
LUNG_NSCLC_LUSC	Regulation of cell-substrate junction assembly →	+0.110	+2.032	.005	.002	2	10
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.139	+1.652	.006	.002	3	9
LIVER	Actin filament depolymerization →	+0.176	+1.643	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,108 associations by consensus.

Intracellular transport of virus by NEGR1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →