NEFL

Across TCGA cell cohorts, NEFL RNA expression is significantly associated with the go_rna of many other GO terms, with 2,251 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible NEFL-associated GO terms across cancer lineages are Neurofilament bundle assembly, Postsynaptic intermediate filament cytoskeleton organization, and Regulation of microtubule cytoskeleton organization. Each is linked with NEFL in more than 15 cancer types. Because this analysis shows association rather than direction, both NEFL-to-partner and partner-to-NEFL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neurofilament bundle assembly grouped by NEFL-low versus NEFL-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEFL→partner) and Y-score (partner→NEFL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Neurofilament bundle assembly →	+1.942	+4.385	<.001	<.001	3	16
OESOPHAGUS	Postsynaptic intermediate filament cytoskeleton organization →	+1.968	+4.308	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of microtubule cytoskeleton organization →	+0.057	+4.446	.009	<.001	3	8
OESOPHAGUS	Tetrapyrrole biosynthetic process →	+0.075	+2.237	.006	.007	3	8
OESOPHAGUS	Porphyrin-containing compound biosynthetic process →	+0.075	+2.237	.006	.007	3	8
LUNG_NSCLC_LUSC	Regulation of stem cell population maintenance →	+0.088	+4.375	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,251 associations by consensus.

Neurofilament bundle assembly by NEFL expression — OESOPHAGUS

Explore this box plot interactively →