NEDD9

Across TCGA patient cohorts, NEDD9 mutation is significantly associated with the RNA expression of many other genes, with 4,562 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NEDD9-associated genes across cancer lineages are MRPL17, CCL4, and PSMA3. Each is linked with NEDD9 in more than 3 cancer types. Because this analysis shows association rather than direction, both NEDD9-to-partner and partner-to-NEDD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL17 grouped by NEDD9-low versus NEDD9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEDD9→partner) and Y-score (partner→NEDD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MRPL17 →	+0.373	+3.021	<.001	<.001	3	4
COAD	CCL4 →	+1.321	+3.472	<.001	.002	3	3
COAD	PSMA3 →	+0.509	+3.730	<.001	<.001	3	3
COAD	GABRE →	-1.127	-3.449	<.001	.005	3	3
COAD	TLE6 →	+0.906	+3.834	<.001	<.001	2	4
UCEC	GPN3 →	+0.507	+2.169	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,562 associations by consensus.

MRPL17 by NEDD9 expression — UCEC

Explore this box plot interactively →