NEDD9

Across TCGA cell cohorts, NEDD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,079 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NEDD9-associated GO terms across cancer lineages are Small GTPase-mediated signal transduction, Endothelial cell-cell adhesion, and Signal transduction in absence of ligand. Each is linked with NEDD9 in more than 11 cancer types. Because this analysis shows association rather than direction, both NEDD9-to-partner and partner-to-NEDD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Small GTPase-mediated signal transduction grouped by NEDD9-low versus NEDD9-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEDD9→partner) and Y-score (partner→NEDD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Small GTPase-mediated signal transduction →	+0.052	+1.785	<.001	<.001	3	12
BLOOD_Lymphoma	Endothelial cell-cell adhesion →	+0.874	+1.145	<.001	.004	3	12
STOMACH	Signal transduction in absence of ligand →	+0.104	+2.293	<.001	<.001	3	11
BLOOD_Lymphoma	Negative regulation of respiratory burst involved in inflammatory response →	+0.150	+2.259	<.001	<.001	3	11
BLOOD_Lymphoma	Negative regulation of respiratory burst →	+0.150	+2.259	<.001	<.001	3	11
URINARY_TRACT	Positive regulation of cell-cell adhesion →	+0.085	+2.908	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,079 associations by consensus.

Small GTPase-mediated signal transduction by NEDD9 expression — BONE

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