NEDD9

Across TCGA cell cohorts, NEDD9 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NEDD9-associated genes across cancer lineages are OR10W1, OR52H1, and ADAM2. Each is linked with NEDD9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEDD9-to-partner and partner-to-NEDD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by NEDD9-low versus NEDD9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEDD9→partner) and Y-score (partner→NEDD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.016	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR52H1 →	+0.020	+3.347	.003	.005	3	1
BLOOD_Lymphoma	ADAM2 →	+0.158	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	FCN2 →	+0.044	+3.714	<.001	.006	3	1
BLOOD_Lymphoma	MUC22 →	+0.064	+3.714	<.001	.006	3	1
SKIN	C16orf92 →	+0.056	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

OR10W1 by NEDD9 expression — LARGE_INTESTINE

Explore this box plot interactively →