NEDD1

Across TCGA cell cohorts, NEDD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,759 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NEDD1-associated GO terms across cancer lineages are Protein localization to chromosome, Mitotic sister chromatid segregation, and Nuclear chromosome segregation. Each is linked with NEDD1 in more than 18 cancer types. Because this analysis shows association rather than direction, both NEDD1-to-partner and partner-to-NEDD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome grouped by NEDD1-low versus NEDD1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NEDD1→partner) and Y-score (partner→NEDD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to chromosome →	+0.138	+0.956	<.001	<.001	3	19
OESOPHAGUS	Mitotic sister chromatid segregation →	+0.121	+0.696	.004	.002	3	18
KIDNEY	Nuclear chromosome segregation →	+0.108	+1.268	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of centrosome duplication →	+0.104	+0.979	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cell cycle process →	+0.086	+1.090	<.001	<.001	3	18
OESOPHAGUS	Regulation of DNA damage checkpoint →	+0.118	+0.941	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,759 associations by consensus.

Protein localization to chromosome by NEDD1 expression — OESOPHAGUS

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