NECTIN2

Across TCGA patient cohorts, NECTIN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,506 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NECTIN2-associated proteins across cancer lineages are PPP1R37, AZU1, and ELANE. Each is linked with NECTIN2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NECTIN2-to-partner and partner-to-NECTIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECTIN2 versus PPP1R37 in PDAC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NECTIN2→partner) and Y-score (partner→NECTIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PPP1R37 →	+0.281	+0.584	<.001	<.001	3	5
GBM	AZU1 →	+1.040	+0.424	<.001	.005	3	5
COAD	ELANE →	+0.796	+0.623	.003	<.001	3	4
CCRCC	C1R →	+0.600	+0.386	.001	.002	3	4
GBM	S100A12 →	+1.422	+0.622	<.001	<.001	3	4
GBM	MPO →	+1.142	+0.501	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,506 associations by consensus.

NECTIN2 vs PPP1R37 — PDAC

Explore this scatter interactively →