NECAP1

Across TCGA patient cohorts, NECAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,488 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NECAP1-associated genes across cancer lineages are LPCAT3, PLEKHO1, and COLGALT1. Each is linked with NECAP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NECAP1-to-partner and partner-to-NECAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECAP1 versus LPCAT3 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NECAP1→partner) and Y-score (partner→NECAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LPCAT3 →	+0.608	+0.268	.002	.005	3	5
OV	PLEKHO1 →	-0.583	-0.436	.008	<.001	3	5
BRCA	COLGALT1 →	-0.561	-0.302	<.001	<.001	3	5
HNSC	PXDN →	-1.004	-0.210	<.001	<.001	3	5
HNSC	VGLL4 →	-0.450	-0.115	<.001	.005	3	5
OV	COPS7A →	+0.735	+0.401	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,488 associations by consensus.

NECAP1 vs LPCAT3 — OV

Explore this scatter interactively →