NECAP1

Across TCGA cell cohorts, NECAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,048 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NECAP1-associated GO terms across cancer lineages are Transcription elongation-coupled chromatin remodeling, Negative regulation of chromosome condensation, and Positive regulation of pentose-phosphate shunt. Each is linked with NECAP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both NECAP1-to-partner and partner-to-NECAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation-coupled chromatin remodeling grouped by NECAP1-low versus NECAP1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NECAP1→partner) and Y-score (partner→NECAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Transcription elongation-coupled chromatin remodeling →	+0.102	+0.835	<.001	.007	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.157	+0.914	.003	<.001	3	11
SKIN	Positive regulation of pentose-phosphate shunt →	+0.150	+0.570	<.001	<.001	3	11
BONE	Oocyte growth →	+0.199	+0.546	<.001	.001	3	11
LARGE_INTESTINE	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.096	+0.798	<.001	<.001	3	10
BONE	Negative regulation of gene expression, epigenetic →	+0.080	+0.561	.005	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,048 associations by consensus.

Transcription elongation-coupled chromatin remodeling by NECAP1 expression — BLOOD_Myeloma

Explore this box plot interactively →