NECAB2

Across TCGA patient cohorts, NECAB2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,774 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NECAB2-associated genes across cancer lineages are SNRPD3, PRODH, and SEZ6L. Each is linked with NECAB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NECAB2-to-partner and partner-to-NECAB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECAB2 versus SNRPD3 in GBM, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NECAB2→partner) and Y-score (partner→NECAB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.406	+0.749	<.001	.003	3	1
GBM	PRODH →	+0.771	+0.758	<.001	<.001	3	1
GBM	SEZ6L →	+1.108	+0.504	.003	.003	3	1
GBM	LGALS1 →	-0.642	-0.624	.003	.005	3	1
GBM	SOX10 →	+1.389	+0.974	<.001	<.001	3	1
GBM	SLC16A8 →	+0.602	+0.739	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,774 associations by consensus.

NECAB2 vs SNRPD3 — GBM

Explore this scatter interactively →