NECAB1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NECAB1 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NECAB1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NECAB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NECAB1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD and LSCC are the cancer types where NECAB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileAll1.0000.450.0124view →
LSCCDFSMedianAll0.6221.000.0261view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NECAB1–LUAD (DFS)

Kaplan–Meier survival curve for NECAB1 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration