NEAT1

Across TCGA patient cohorts, NEAT1 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible NEAT1-associated genes across cancer lineages are IGKV2OR2-7D, SEPTIN14P17, and RNU6-1315P. Each is linked with NEAT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NEAT1-to-partner and partner-to-NEAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGKV2OR2-7D grouped by NEAT1-low versus NEAT1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NEAT1→partner) and Y-score (partner→NEAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	IGKV2OR2-7D →	+0.155	+5.544	<.001	.004	3	1
LIHC	SEPTIN14P17 →	+0.216	+6.305	<.001	.001	3	1
LIHC	RNU6-1315P →	+0.349	+5.186	<.001	.007	3	1
LIHC	IGKV3-25 →	+0.349	+6.676	<.001	<.001	3	1
LIHC	IGHVII-22-1 →	+0.387	+5.447	<.001	.005	3	1
LIHC	IGHVII-51-2 →	+0.252	+5.447	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

IGKV2OR2-7D by NEAT1 expression — LIHC

Explore this box plot interactively →