NDUFV3

Across TCGA patient cohorts, NDUFV3 mutation is significantly associated with the RNA expression of many other genes, with 364 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFV3-associated genes across cancer lineages are NAMPTP3, RNA5SP360, and RNU6-293P. Each is linked with NDUFV3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDUFV3-to-partner and partner-to-NDUFV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NAMPTP3 grouped by NDUFV3-low versus NDUFV3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV3→partner) and Y-score (partner→NDUFV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NAMPTP3 →	+0.215	+4.487	.001	.005	3	3
BRCA	RNA5SP360 →	+0.346	+7.243	<.001	<.001	3	2
HNSC	RNU6-293P →	+0.319	+4.505	<.001	.009	3	2
UCEC	RTCB →	+0.566	+3.638	.007	.001	3	2
UCEC	POLDIP3 →	+0.548	+3.210	.006	.009	3	2
UCEC	TXN2 →	+0.379	+2.556	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 364 associations by consensus.

NAMPTP3 by NDUFV3 expression — BRCA

Explore this box plot interactively →