NDUFV3

Across TCGA patient cohorts, NDUFV3 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFV3-associated genes across cancer lineages are ATM, Acetyl-a-Tubulin-Lys40, and JNK2. Each is linked with NDUFV3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFV3-to-partner and partner-to-NDUFV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by NDUFV3-low versus NDUFV3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV3→partner) and Y-score (partner→NDUFV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.807	-3.321	<.001	.010	3	2
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.589	+2.817	.027	.036	3	1
UCEC	JNK2 →	+0.347	+2.817	<.001	.036	3	1
UCEC	Ku80 →	+0.277	+2.183	.025	.035	3	1
UCEC	VEGFR2 →	+0.319	+2.183	.040	.035	3	1
UCEC	14-3-3_zeta →	+0.295	+2.196	.006	.034	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ATM by NDUFV3 expression — UCEC

Explore this box plot interactively →