NDUFV2

Across TCGA patient cohorts, NDUFV2 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFV2-associated genes across cancer lineages are Ku80, Notch1, and p27_pT198. Each is linked with NDUFV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFV2-to-partner and partner-to-NDUFV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by NDUFV2-low versus NDUFV2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV2→partner) and Y-score (partner→NDUFV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.346	+3.183	.007	.010	3	1
UCEC	Notch1 →	+0.251	+2.820	.001	.035	3	1
UCEC	p27_pT198 →	+0.138	+3.000	.018	.036	3	1
UCEC	ACC1 →	+0.481	+3.169	.015	.020	2	1
UCEC	EGFR_pY1068 →	-0.345	-3.169	.012	.020	1	1
UCEC	Gab2 →	+0.502	+3.169	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Ku80 by NDUFV2 expression — UCEC

Explore this box plot interactively →