NDUFV2

Across TCGA cell cohorts, NDUFV2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,110 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NDUFV2-associated GO terms across cancer lineages are Regulation of mitochondrial transcription, Negative regulation of macrophage colony-stimulating factor signaling pathway, and Mitochondrial inner membrane fusion. Each is linked with NDUFV2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NDUFV2-to-partner and partner-to-NDUFV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial transcription grouped by NDUFV2-low versus NDUFV2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV2→partner) and Y-score (partner→NDUFV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of mitochondrial transcription →	+0.147	+0.633	<.001	.003	3	14
LUNG_SCLC	Negative regulation of macrophage colony-stimulating factor signaling pathway →	+0.228	+0.751	<.001	<.001	3	14
LUNG_SCLC	Mitochondrial inner membrane fusion →	+0.112	+0.981	.001	<.001	3	13
LUNG_SCLC	Regulation of mitochondrial DNA replication →	+0.134	+0.798	<.001	<.001	3	11
LIVER	Mitochondrial protein processing →	+0.168	+1.287	.002	.001	3	9
LUNG_NSCLC_LUSC	RNA capping →	+0.084	+0.964	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,110 associations by consensus.

Regulation of mitochondrial transcription by NDUFV2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →