NDUFV1

Across TCGA pan-cancer cohorts, NDUFV1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NDUFV1 data layer compared with 27 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NDUFV1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NDUFV1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where NDUFV1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	1.000	0.890	.003	23	view →
HNSC	DFS	Tertile	All	1.000	0.317	.028	11	view →
PDAC	OS	Tertile	All	0.590	0.324	.026	7	view →
GBM	OS	Median	All	0.862	0.769	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NDUFV1–CCRCC (OS)

Open the CCRCC breakdown →