NDUFV1

Across TCGA patient cohorts, NDUFV1 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFV1-associated genes across cancer lineages are EGFR_pY1068, MSH2, and 14-3-3_beta. Each is linked with NDUFV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFV1-to-partner and partner-to-NDUFV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by NDUFV1-low versus NDUFV1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV1→partner) and Y-score (partner→NDUFV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.235	-2.247	.010	.001	3	2
UCEC	MSH2 →	-0.273	-1.848	.001	.049	3	2
UCEC	14-3-3_beta →	-0.083	-2.558	.024	.010	3	1
UCEC	ACC1 →	+0.283	+1.887	.034	.029	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.395	+1.710	.034	.025	3	1
UCEC	JNK_pT183_Y185 →	-0.201	-3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

EGFR_pY1068 by NDUFV1 expression — UCEC

Explore this box plot interactively →