NDUFV1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NDUFV1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFV1-associated genes across cancer lineages are MYL7, APOL5, and SCN1A. Each is linked with NDUFV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFV1-to-partner and partner-to-NDUFV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL7 grouped by NDUFV1-low versus NDUFV1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFV1→partner) and Y-score (partner→NDUFV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaMYL7 →+0.065+3.339<.001.00631
BLOOD_LeukemiaAPOL5 →+0.010+3.475.007.00631
BLOOD_LeukemiaSCN1A →+0.482+3.847<.001.00431
BLOOD_LeukemiaAQP12A →+0.084+3.684<.001.00431
BLOOD_LeukemiaSMIM23 →+0.015+4.569<.001.00331
BLOOD_LeukemiaOR13C3 →+0.021+3.289<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

MYL7 by NDUFV1 expression — BLOOD_Leukemia

Box plot of MYL7 in NDUFV1-low vs NDUFV1-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration