NDUFS5P5

Across TCGA pan-cancer cohorts, NDUFS5P5 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NDUFS5P5 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NDUFS5P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NDUFS5P5 expression acts as an unfavorable survival marker, although some lineages such as HNSC and ESCA show a favorable association.

LIHC, KICH, and HNSC are the cancer types where NDUFS5P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	II,III,IV	0.167	0.643	<.001	96	view →
KICH	DFS	Tertile	All	0.427	0.883	<.001	60	view →
HNSC	DFS	Tertile	All	0.762	0.603	.015	51	view →
UCS	DFS	Tertile	IV	0.290	0.752	.028	36	view →
UCEC	DFS	Tertile	III,IV	0.592	0.818	.016	36	view →
MESO	DFS	Tertile	All	0.153	0.479	.025	27	view →
KIRC	DFS	Quartile	III,IV	0.298	0.520	.007	25	view →
UVM	OS	Tertile	All	0.248	0.769	.007	18	view →
LUSC	DFS	Tertile	III,IV	0.152	0.781	.004	18	view →
ACC	DFS	Tertile	III,IV	0.048	0.457	.015	18	view →
COAD	OS	Tertile	II,III,IV	0.270	0.692	.006	15	view →
ESCA	DFS	Quartile	IV	0.826	0.306	.040	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NDUFS5P5–LIHC (OS)

Open the LIHC breakdown →