NDUFS4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFS4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,488 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NDUFS4-associated genes across cancer lineages are TMSB10, GALNTL6, and E2F3. Each is linked with NDUFS4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDUFS4-to-partner and partner-to-NDUFS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFS4 versus TMSB10 in BRCA, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS4→partner) and Y-score (partner→NDUFS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCATMSB10 →-0.959-0.538<.001<.00134
GBMGALNTL6 →+0.345+0.325<.001<.00134
BRCAE2F3 →-0.562-0.432<.001<.00133
BRCAUBE2E3 →-0.698-0.323<.001<.00133
LUADWDHD1 →-0.468-0.160.002.00733
GBMHTR2A-AS1 →+0.575+0.418<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,488 associations by consensus.

NDUFS4 vs TMSB10 — BRCA

Per-sample scatter of NDUFS4 vs TMSB10 in BRCA (Pearson r = -0.47).

Explore this scatter interactively →

Exploration