NDUFS4

Across TCGA patient cohorts, NDUFS4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFS4-associated genes across cancer lineages are Endothelial cells, pDC, and Myocytes. Each is linked with NDUFS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS4-to-partner and partner-to-NDUFS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by NDUFS4-low versus NDUFS4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS4→partner) and Y-score (partner→NDUFS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.045	-3.279	.024	.011	3	1
UCEC	pDC →	+0.080	+3.032	.001	.018	3	1
UCEC	Myocytes →	+0.044	+3.364	.010	.005	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by NDUFS4 expression — UCEC

Explore this box plot interactively →