NDUFS4

Across TCGA cell cohorts, NDUFS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,237 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NDUFS4-associated GO terms across cancer lineages are Lactation, Regulation of centriole elongation, and Protein linear polyubiquitination. Each is linked with NDUFS4 in more than 7 cancer types. Because this analysis shows association rather than direction, both NDUFS4-to-partner and partner-to-NDUFS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lactation grouped by NDUFS4-low versus NDUFS4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS4→partner) and Y-score (partner→NDUFS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Lactation →	-0.166	-1.084	.001	.009	3	8
OVARY	Regulation of centriole elongation →	+0.090	+0.748	<.001	<.001	3	8
PANCREAS	Protein linear polyubiquitination →	-0.139	-0.600	<.001	<.001	3	8
SOFT_TISSUE	Vesicle coating →	+0.075	+0.882	.003	.001	3	8
BLOOD_Lymphoma	Insulin processing →	+0.142	+0.932	<.001	<.001	3	8
BLOOD_Lymphoma	Enzyme-directed rRNA pseudouridine synthesis →	-0.104	-0.775	<.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,237 associations by consensus.

Lactation by NDUFS4 expression — LUNG_NSCLC_LUSC

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