NDUFC2

Across TCGA pan-cancer cohorts, NDUFC2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NDUFC2 data layer compared with 19 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NDUFC2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFC2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, PDAC, and LSCC are the cancer types where NDUFC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.821	0.645	.014	6	view →
PDAC	DFS	Median	II,III,IV	0.265	0.469	.009	5	view →
LSCC	OS	Tertile	All	1.000	0.896	.018	5	view →
LUAD	DFS	Median	All	0.862	0.935	.048	1	view →
HNSC	DFS	Median	II,III,IV	0.895	0.976	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NDUFC2–CCRCC (DFS)

Open the CCRCC breakdown →