NDUFB9

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB9 mutation is significantly associated with the RNA expression of many other genes, with 323 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NDUFB9-associated genes across cancer lineages are PCDH9-AS1, SLC30A6P1, and MIR6074. Each is linked with NDUFB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB9-to-partner and partner-to-NDUFB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDH9-AS1 grouped by NDUFB9-low versus NDUFB9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB9→partner) and Y-score (partner→NDUFB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMPCDH9-AS1 →+0.021+2.684<.001.00332
COADSLC30A6P1 →+0.994+5.516<.001.00432
SKCMMIR6074 →+0.087+3.103<.001.00432
SKCMMIR6070 →+0.109+1.879.002.00832
SKCMSNORD3C →+0.012+3.369<.001.00232
SKCMOR8B12 →+0.028+1.936<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 323 associations by consensus.

PCDH9-AS1 by NDUFB9 expression — SKCM

Box plot of PCDH9-AS1 in NDUFB9-low vs NDUFB9-high samples in SKCM.

Explore this box plot interactively →

Exploration