NDUFB9

Across TCGA patient cohorts, NDUFB9 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NDUFB9-associated genes across cancer lineages are EGFR_pY1068, ER-alpha, and A-Raf_pS299. Each is linked with NDUFB9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB9-to-partner and partner-to-NDUFB9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by NDUFB9-low versus NDUFB9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB9→partner) and Y-score (partner→NDUFB9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	EGFR_pY1068 →	-0.221	-4.070	<.001	<.001	3	1
SKCM	ER-alpha →	-0.161	-1.584	.015	.018	3	1
SKCM	A-Raf_pS299 →	-0.118	-3.459	.021	.004	3	1
SKCM	GAPDH →	+0.543	+2.000	.009	.027	3	1
SKCM	GATA6 →	-0.185	-1.792	.022	.023	3	1
SKCM	JNK_pT183_Y185 →	-0.110	-2.459	.024	.017	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

EGFR_pY1068 by NDUFB9 expression — SKCM

Explore this box plot interactively →