Across TCGA pan-cancer cohorts, NDUFB5P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NDUFB5P1’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NDUFB5P1 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFB5P1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUSC and KIRP are the cancer types where NDUFB5P1 tumor–normal differential expression is most reproducible.