NDUFB4P6

Across TCGA pan-cancer cohorts, NDUFB4P6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NDUFB4P6 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher NDUFB4P6 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFB4P6 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

SKCM, ACC, and BRCA are the cancer types where NDUFB4P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	II,III,IV	0.781	0.626	.003	54	view →
ACC	DFS	Tertile	II,III,IV	0.122	0.477	.018	45	view →
BRCA	DFS	Median	IV	0.793	0.287	<.001	36	view →
MESO	OS	Quartile	III,IV	0.808	0.211	.007	27	view →
COAD	DFS	Median	All	0.593	0.744	.009	22	view →
KIRP	OS	Quartile	IV	0.037	0.470	.028	18	view →
READ	DFS	Median	III,IV	0.263	0.696	.002	15	view →
LIHC	OS	Tertile	III,IV	0.307	0.662	.001	9	view →
HNSC	OS	Tertile	II,III,IV	0.592	0.706	.027	7	view →
SARC	OS	Tertile	All	0.897	0.787	.037	6	view →
UVM	OS	Quartile	II,III,IV	0.825	0.573	.023	5	view →
LUSC	DFS	Tertile	III,IV	0.236	0.729	.039	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NDUFB4P6–SKCM (DFS)

Open the SKCM breakdown →