NDUFB4P11

Across TCGA pan-cancer cohorts, NDUFB4P11 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of NDUFB4P11’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NDUFB4P11 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFB4P11 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

KICH, BRCA, and KIRC are the cancer types where NDUFB4P11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFB4P11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.024	<.001	10	view →
BRCA	All	III,IV	−0.447	<.001	8	view →
KIRC	Male	All	−0.620	<.001	7	view →
COAD	Female	All	−0.032	.011	5	view →
LUSC	All	All	+0.373	<.001	4	view →
PRAD	All	All	−0.149	<.001	2	view →
STAD	All	All	+0.110	.031	2	view →
PAAD	Male	All	−0.084	.003	2	view →
CHOL	All	All	+0.148	.041	1	view →
LUAD	All	II,III,IV	−0.063	.032	1	view →
THCA	Male	All	−0.051	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

NDUFB4P11–KICH

Open the KICH breakdown →