NDUFB3

Across TCGA pan-cancer cohorts, NDUFB3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NDUFB3 data layer compared with 28 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NDUFB3 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFB3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, GBM, and LUAD are the cancer types where NDUFB3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.878	0.653	.004	24	view →
GBM	DFS	Tertile	All	0.839	0.639	.041	4	view →
LUAD	DFS	Median	III,IV	0.690	0.305	.032	2	view →
PDAC	OS	Quartile	III,IV	0.936	0.525	.032	2	view →
HNSC	DFS	Tertile	II,III,IV	0.889	0.988	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NDUFB3–CCRCC (DFS)

Open the CCRCC breakdown →