NDUFB3

Across TCGA patient cohorts, NDUFB3 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NDUFB3-associated genes across cancer lineages are RNU6-503P, RNU6-521P, and MIR654. Each is linked with NDUFB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB3-to-partner and partner-to-NDUFB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-503P grouped by NDUFB3-low versus NDUFB3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB3→partner) and Y-score (partner→NDUFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-503P →	+0.361	+7.741	<.001	.009	3	2
COAD	RNU6-521P →	+0.782	+7.741	<.001	.009	3	2
STAD	MIR654 →	+0.375	+6.226	<.001	.001	3	2
STAD	MIR660 →	+0.840	+5.026	<.001	.009	3	2
STAD	RNU2-47P →	+0.726	+5.366	<.001	.005	3	2
STAD	MIR548W →	+0.617	+5.026	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

RNU6-503P by NDUFB3 expression — COAD

Explore this box plot interactively →