NDUFB3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFB3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NDUFB3-associated genes across cancer lineages are CD4+ Tem, Osteoblast, and GMP. Each is linked with NDUFB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB3-to-partner and partner-to-NDUFB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by NDUFB3-low versus NDUFB3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB3→partner) and Y-score (partner→NDUFB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADCD4+ Tem →+0.013+4.450.027.01931
STADOsteoblast →+0.030+3.669.014.04931
SKCMGMP →+0.075+3.806<.001.01831
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tem by NDUFB3 expression — STAD

Box plot of CD4+ Tem in NDUFB3-low vs NDUFB3-high samples in STAD.

Explore this box plot interactively →

Exploration