NDUFB2

Across TCGA patient cohorts, NDUFB2 mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NDUFB2-associated genes across cancer lineages are MIR6871, CTBP2P9, and GUSBP17. Each is linked with NDUFB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB2-to-partner and partner-to-NDUFB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6871 grouped by NDUFB2-low versus NDUFB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB2→partner) and Y-score (partner→NDUFB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR6871 →	+0.796	+4.032	<.001	.005	3	1
SKCM	CTBP2P9 →	+0.025	+4.495	.003	.007	3	1
SKCM	GUSBP17 →	+0.282	+4.603	<.001	.001	3	1
SKCM	RNU7-141P →	+0.450	+3.838	.003	.006	3	1
SKCM	RPL9P6 →	+0.050	+4.495	<.001	.007	3	1
SKCM	RN7SL702P →	+0.174	+5.356	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

MIR6871 by NDUFB2 expression — SKCM

Explore this box plot interactively →