NDUFB11

Across TCGA patient cohorts, NDUFB11 mutation is significantly associated with the RNA expression of many other genes, with 109 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB11-associated genes across cancer lineages are IGHV3OR16-8, TAF9, and SEC24D. Each is linked with NDUFB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB11-to-partner and partner-to-NDUFB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHV3OR16-8 grouped by NDUFB11-low versus NDUFB11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB11→partner) and Y-score (partner→NDUFB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHV3OR16-8 →	+0.690	+2.950	.006	.003	3	1
UCEC	TAF9 →	+0.592	+3.191	.002	.009	3	1
UCEC	SEC24D →	+0.897	+3.595	.001	.001	3	1
UCEC	BAG3 →	+0.732	+3.584	.002	.003	3	1
UCEC	EOMES →	+0.512	+3.584	.008	.003	3	1
UCEC	GFM2 →	+0.689	+3.257	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 109 associations by consensus.

IGHV3OR16-8 by NDUFB11 expression — UCEC

Explore this box plot interactively →