NDUFB11

Across TCGA patient cohorts, NDUFB11 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFB11-associated genes across cancer lineages are Annexin-1, p62 Lck ligand, and ERK2. Each is linked with NDUFB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFB11-to-partner and partner-to-NDUFB11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by NDUFB11-low versus NDUFB11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFB11→partner) and Y-score (partner→NDUFB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.711	+3.000	.019	.037	3	1
UCEC	p62 Lck ligand →	+0.508	+2.817	.006	.036	2	1
UCEC	ERK2 →	+0.307	+3.000	.005	.037	1	1
UCEC	XBP1 →	-0.307	-3.000	<.001	.037	1	1
UCEC	DJ-1 →	+0.327	+3.000	<.001	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Annexin-1 by NDUFB11 expression — UCEC

Explore this box plot interactively →