NDUFAF7

Across TCGA patient cohorts, NDUFAF7 mutation is significantly associated with the RNA expression of many other genes, with 1,624 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFAF7-associated genes across cancer lineages are RNA5SP421, MIR4294, and CTHRC1P1. Each is linked with NDUFAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF7-to-partner and partner-to-NDUFAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP421 grouped by NDUFAF7-low versus NDUFAF7-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF7→partner) and Y-score (partner→NDUFAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP421 →	+0.471	+4.853	.009	.004	3	2
LUSC	MIR4294 →	+0.613	+3.781	<.001	.007	3	2
LUSC	CTHRC1P1 →	+0.099	+4.795	<.001	.001	3	2
UCEC	TRAJ57 →	+0.452	+2.425	<.001	.001	3	2
UCEC	TRAJ6 →	+0.651	+2.078	<.001	.001	3	2
UCEC	LINC01072 →	+0.097	+2.266	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,624 associations by consensus.

RNA5SP421 by NDUFAF7 expression — LUSC

Explore this box plot interactively →