NDUFAF7

Across TCGA patient cohorts, NDUFAF7 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFAF7-associated genes across cancer lineages are TIGAR, Beclin, and EGFR_pY1068. Each is linked with NDUFAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF7-to-partner and partner-to-NDUFAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIGAR grouped by NDUFAF7-low versus NDUFAF7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF7→partner) and Y-score (partner→NDUFAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIGAR →	+0.134	+2.933	.038	<.001	3	2
UCEC	Beclin →	+0.095	+4.000	.017	<.001	3	2
UCEC	EGFR_pY1068 →	-0.258	-2.584	.015	.010	3	1
UCEC	eIF4E →	+0.187	+3.169	.037	.019	3	1
UCEC	A-Raf_pS299 →	-0.108	-2.321	.032	.034	3	1
UCEC	GSK-3_pS9 →	-0.440	-2.321	.010	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

TIGAR by NDUFAF7 expression — UCEC

Explore this box plot interactively →