NDUFAF7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NDUFAF7 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NDUFAF7-associated genes across cancer lineages are OR10A5, NPAP1, and CFHR2. Each is linked with NDUFAF7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF7-to-partner and partner-to-NDUFAF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10A5 grouped by NDUFAF7-low versus NDUFAF7-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF7→partner) and Y-score (partner→NDUFAF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTOR10A5 →+0.039+5.169<.001.00531
BREASTNPAP1 →+0.013+5.169<.001.00531
LARGE_INTESTINECFHR2 →+0.057+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10A5 by NDUFAF7 expression — BREAST

Box plot of OR10A5 in NDUFAF7-low vs NDUFAF7-high samples in BREAST.

Explore this box plot interactively →

Exploration