NDUFAF6

Across TCGA patient cohorts, NDUFAF6 mutation is significantly associated with the RNA expression of many other genes, with 1,238 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFAF6-associated genes across cancer lineages are RN7SKP181, RNA5SP325, and RNY1P1. Each is linked with NDUFAF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF6-to-partner and partner-to-NDUFAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by NDUFAF6-low versus NDUFAF6-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF6→partner) and Y-score (partner→NDUFAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RN7SKP181 →	+0.136	+7.924	.006	.008	3	2
UCEC	RNA5SP325 →	+1.165	+2.448	<.001	<.001	3	2
UCEC	RNY1P1 →	+0.162	+2.920	.001	.008	3	2
UCEC	RNA5SP353 →	+0.512	+2.359	<.001	.005	3	2
UCEC	RNA5SP88 →	+0.433	+2.864	<.001	.003	3	2
UCEC	RNU6-1241P →	+0.173	+3.038	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,238 associations by consensus.

RN7SKP181 by NDUFAF6 expression — LUSC

Explore this box plot interactively →