NDUFAF6

Across TCGA cell cohorts, NDUFAF6 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NDUFAF6-associated genes across cancer lineages are GSG1L2, MAGEB4, and FTHL17. Each is linked with NDUFAF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF6-to-partner and partner-to-NDUFAF6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSG1L2 grouped by NDUFAF6-low versus NDUFAF6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF6→partner) and Y-score (partner→NDUFAF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
LARGE_INTESTINE	MAGEB4 →	+0.029	+5.415	<.001	.004	3	1
LARGE_INTESTINE	FTHL17 →	+0.081	+5.415	<.001	.004	3	1
LARGE_INTESTINE	STRA8 →	+0.215	+5.415	<.001	.004	3	1
LARGE_INTESTINE	ZNF804B →	+0.022	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR2J1 →	+0.006	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

GSG1L2 by NDUFAF6 expression — BLOOD_Leukemia

Explore this box plot interactively →