NDUFAF5

Across TCGA pan-cancer cohorts, NDUFAF5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NDUFAF5 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NDUFAF5 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFAF5 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, PDAC, and GBM are the cancer types where NDUFAF5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	III,IV	1.000	0.790	.032	18	view →
PDAC	OS	Tertile	III,IV	0.392	1.000	.013	9	view →
GBM	OS	Median	All	0.867	0.764	.027	8	view →
LSCC	DFS	Quartile	All	0.228	0.825	.010	6	view →
CCRCC	DFS	Median	III,IV	0.434	0.723	.013	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NDUFAF5–COAD (DFS)

Open the COAD breakdown →