NDUFAF5

Across TCGA patient cohorts, NDUFAF5 protein abundance is significantly associated with the RNA expression of many other genes, with 10,312 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NDUFAF5-associated genes across cancer lineages are EDNRB, CASP4LP, and SEC23B. Each is linked with NDUFAF5 in more than 3 cancer types. Because this analysis shows association rather than direction, both NDUFAF5-to-partner and partner-to-NDUFAF5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFAF5 versus EDNRB in CCRCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF5→partner) and Y-score (partner→NDUFAF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EDNRB →	-0.874	-0.263	<.001	<.001	3	4
CCRCC	CASP4LP →	-0.606	-0.288	<.001	<.001	3	4
OV	SEC23B →	+0.483	+0.381	.006	.009	3	3
OV	PLVAP →	-1.058	-0.314	.004	.006	3	3
BRCA	CABP4 →	-0.837	-0.256	<.001	.003	3	3
CCRCC	TIE1 →	-0.792	-0.339	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,312 associations by consensus.

NDUFAF5 vs EDNRB — CCRCC

Explore this scatter interactively →