NDUFAF5

Across TCGA patient cohorts, NDUFAF5 mutation is significantly associated with the RNA expression of many other genes, with 346 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFAF5-associated genes across cancer lineages are RN7SL785P, RNU6-66P, and ARL6IP1P2. Each is linked with NDUFAF5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF5-to-partner and partner-to-NDUFAF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL785P grouped by NDUFAF5-low versus NDUFAF5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF5→partner) and Y-score (partner→NDUFAF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL785P →	+0.196	+2.717	<.001	.006	3	2
UCEC	RNU6-66P →	+0.263	+3.750	<.001	.002	3	2
UCEC	ARL6IP1P2 →	+0.306	+3.480	.004	.002	3	2
UCEC	SNRPFP3 →	+0.099	+4.414	<.001	.004	3	2
UCEC	MTATP6P21 →	+0.230	+2.481	.005	.006	3	2
SKCM	RPS27P22 →	+0.434	+4.241	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 346 associations by consensus.

RN7SL785P by NDUFAF5 expression — UCEC

Explore this box plot interactively →