NDUFAF4P3

Across TCGA pan-cancer cohorts, NDUFAF4P3 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of NDUFAF4P3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NDUFAF4P3 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFAF4P3 is over-expressed in tumor, although a few such as KIRC and LUSC show the opposite, repressed pattern.

KIRC, LUSC, and KIRP are the cancer types where NDUFAF4P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFAF4P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	III,IV	−0.720	<.001	11	view →
LUSC	All	III,IV	−1.029	<.001	9	view →
KIRP	Male	All	−0.702	<.001	9	view →
BLCA	All	IV	−1.165	<.001	8	view →
LUAD	Female	III,IV	−0.738	<.001	8	view →
UCEC	All	All	−1.013	<.001	6	view →
BRCA	Female	All	−0.811	<.001	6	view →
KICH	Female	All	−0.795	<.001	5	view →
COAD	All	All	−0.291	.002	5	view →
THCA	All	II,III,IV	−0.372	.006	4	view →
LIHC	All	All	+0.200	.002	3	view →
HNSC	All	II,III,IV	−0.140	.011	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

NDUFAF4P3–KIRC

Open the KIRC breakdown →