NDUFAF3

Across TCGA patient cohorts, NDUFAF3 protein abundance is significantly associated with the RNA expression of many other genes, with 11,703 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDUFAF3-associated genes across cancer lineages are NDUFAF4, NBL1, and SAMD12. Each is linked with NDUFAF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NDUFAF3-to-partner and partner-to-NDUFAF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDUFAF3 versus NDUFAF4 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF3→partner) and Y-score (partner→NDUFAF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFAF4 →	+0.766	+0.445	<.001	<.001	3	5
OV	NBL1 →	-1.060	-0.312	.001	.008	3	4
LSCC	SAMD12 →	+1.140	+0.296	<.001	<.001	3	4
BRCA	CTSO →	-0.757	-0.390	<.001	<.001	3	4
OV	LGALS2 →	-0.892	-0.334	.002	.003	3	3
OV	FBXO7 →	-0.411	-0.358	.003	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,703 associations by consensus.

NDUFAF3 vs NDUFAF4 — BRCA

Explore this scatter interactively →