NDUFAF2

Across TCGA patient cohorts, NDUFAF2 mutation is significantly associated with the RNA expression of many other genes, with 113 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFAF2-associated genes across cancer lineages are MIR1227, GPN3P1, and CKS1BP6. Each is linked with NDUFAF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFAF2-to-partner and partner-to-NDUFAF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1227 grouped by NDUFAF2-low versus NDUFAF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFAF2→partner) and Y-score (partner→NDUFAF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR1227 →	+0.424	+2.902	.002	.006	3	2
SKCM	GPN3P1 →	+0.062	+4.328	<.001	.007	3	2
UCEC	CKS1BP6 →	+0.538	+2.867	.002	.009	3	1
UCEC	NUTF2P8 →	+0.176	+3.661	<.001	.001	3	1
UCEC	RPL23AP90 →	+0.490	+3.226	<.001	.002	3	1
UCEC	RPS29P32 →	+0.695	+3.277	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 113 associations by consensus.

MIR1227 by NDUFAF2 expression — UCEC

Explore this box plot interactively →