NDUFAF1

Across TCGA pan-cancer cohorts, NDUFAF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NDUFAF1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NDUFAF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NDUFAF1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, CCRCC, and LUAD are the cancer types where NDUFAF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	1.000	0.837	.005	24	view →
CCRCC	DFS	Median	III,IV	0.821	1.000	.020	6	view →
LUAD	OS	Tertile	II,III,IV	0.827	0.383	.022	4	view →
PDAC	DFS	Tertile	All	0.537	0.252	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NDUFAF1–LSCC (DFS)

Open the LSCC breakdown →