NDUFAB1

Across TCGA pan-cancer cohorts, NDUFAB1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NDUFAB1 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NDUFAB1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDUFAB1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and GBM show a favorable association.

CCRCC, PDAC, and GBM are the cancer types where NDUFAB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.433	0.700	.010	19	view →
PDAC	DFS	Tertile	All	0.777	0.647	.021	12	view →
GBM	OS	Median	All	0.869	0.675	.010	6	view →
LSCC	DFS	Tertile	All	0.916	0.732	.030	4	view →
HNSC	OS	Tertile	All	0.551	0.736	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NDUFAB1–CCRCC (DFS)

Open the CCRCC breakdown →